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Showing posts with label Cell membrane. Show all posts
Showing posts with label Cell membrane. Show all posts

7.13.2009

Landmark Study Finds: Thimerosal Causes Autism Brain Pathology

·New Study Proves Thimerosal Induces Autism-like Neurotoxicity.
·Mitochondrial dysfunction, impaired oxidative-reduction activity, degeneration, and death in human neuronal and fetal cells induced by low-level exposure to thimerosal and other metal compounds.

http://charlieinwonderland.com/?p=1380
http://dprogram.net/2009/07/10/new-study-proves-thimerosal-induces-autism-like-neurotoxicity/
http://www.informaworld.com/smpp/content~content=a910652305~db=all~jumptype=rss
http://www.helpyourautisticchildblog.com/wp-content/uploads/2008/12/auti.gifhttp://www.whale.to/vaccines/thimerosal_infants.jpg
A new study, “A Mitochondrial Dysfunction, Impaired Oxidative-Reduction Activity, Degeneration, and Death in Human Neuronal and Fetal Cells Induced by Low-Level Exposure to Thimerosal and Other Metal Compounds”, published in the most recent issue of the peer-reviewed journal of Toxicology & Environmental Toxicology, confirms a causal connection between Thimerosal and the brain pathology found in patients diagnosed with an autism spectrum disorder (ASD).
[...]
This study showed Thimerosal-induced cellular damage in human neuronal and fetal-cell model systems in a concentration- and time-dependent fashion using Thimerosal at low nanomolar (parts-per-billion) concentrations. These concentrations are comparable to those found in fetal and early infant exposure to mercury from Thimerosal-containing biologics and vaccines in the 1990s and, in some instances, today. These levels induced significant cellular toxicity in the human neuronal and fetal cells studied. The Thimerosal-induced cellular damage was consistent with that found in pathophysiological studies of patients diagnosed with an ASD. In both instances, the studies found significant mitochondrial dysfunction, reduced cellular oxidative-reduction activity, cell degeneration, and cell death.
The present study also revealed that Thimerosal is significantly more toxic than the other metal compounds studied (e.g., aluminum sulfate, methylmercury hydroxide, lead acetate, and mercuric chloride). The explanation for Thimerosal’s greater toxicity than even methylmercury hydroxide (MeHgOH) appears to be the fact that Thimerosal was chemically engineered in the 1920s to be a more highly toxic alkylmercury compound, whose biological transport and intracellular delivery properties were enhanced. Compared to MeHgOH, Thimerosal has: 1) higher aqueous solubility (i.e. ability to dissolve in water and water-based systems); 2) higher solubility in cell membranes (i.e. ability to dissolve in cell membranes); and 3) higher intracellular toxicity (i.e. ability to inactivate essential cell processes) and mercury retention.
Read more...
[Here, the article from dprogram.net]
[And here the study, as published on informaworld.com]
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6.17.2009

New Glimpses of Life’s Puzzling Origins

http://www.nytimes.com/2009/06/16/science/16orig.html?hpw
http://graphics8.nytimes.com/images/2009/06/16/science/16origins-600.jpg
[...]
The origins of life on Earth bristle with puzzle and paradox. Which came first, the proteins of living cells or the genetic information that makes them? How could the metabolism of living things get started without an enclosing membrane to keep all the necessary chemicals together? But if life started inside a cell membrane, how did the necessary nutrients get in?
The questions may seem moot, since life did start somehow. But for the small group of researchers who insist on learning exactly how it started, frustration has abounded. Many once-promising leads have led only to years of wasted effort. Scientists as eminent as Francis Crick, the chief theorist of molecular biology, have quietly suggested that life may have formed elsewhere before seeding the planet, so hard does it seem to find a plausible explanation for its emergence on Earth.
Read all of it...
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